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The Xenograft Barrier Appendix

# Article Information # of Cites
1Phelps CJ, Koike C, Vaught TD, Boone J, Wells KD, Chen SH, Ball S, Specht SM, Polejaeva IA, Monahan JA, Jobst PM, Sharma SM, Lamborn AE, Moore M, Demetris AJ, Trucco M, Starzl TE, Dai Y, Ayares DL: Production of α1,3-galactosyltransferase-deficient pigs. Science 299:411-414, 2003.
http://d-scholarship.pitt.edu/5568/
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2Starzl TE, Fung J, Tzakis A, Todo S, Demetris AJ, Marino IR, Doyle H, Zeevi A, Warty V, Michaels M, Kusne S, Rudert WA, Trucco M: Baboon-to-human liver transplantation. Lancet 341:65-71, 1993.
http://d-scholarship.pitt.edu/4884/
307
3Starzl TE, Marchioro TL, Peters GN, Kirkpatrick CH, Wilson WEC, Porter KA, Rifkind D, Ogden DA, Hitchcock CR, Waddell WR: Renal heterotransplantation from baboon to man: Experience with 6 cases. Transplantation 2:752-776, 1964.
http://d-scholarship.pitt.edu/3473/
173
4Chen G, Qian H, Starzl T, Sun H, Garcia B, Wang X, Wise Y, Liu Y, Xiang Y, Copeman L, Liu W, Jevnikar A, Wall W, Cooper DKC, Murase N, Dai Y, Wang W, Xiong Y, White DJ, Zhong R: Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal- knockout pig kidneys. Nature Med 11:1295-1298, 2005.
http://d-scholarship.pitt.edu/5607/
148
5Lai L, Kang JX, Li R, Wang J, Witt WT, Yong HY, Hao Y, Wax DM, Murphy CN, Rieke A, Samuel M, Linville ML, Korte SW, Evans RW, Starzl TE, Prather RS, Dai Y: Generation of cloned transgenic pigs rich in omega-3 fatty acids. Nature Biotechnol 24:435-436, 2006.
http://d-scholarship.pitt.edu/5611/
140
6Murase N, Starzl TE, Demetris AJ, Valdivia L, Tanabe M, Cramer D, Makowka L: Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs. Transplantation 55:701-708, 1993.
http://d-scholarship.pitt.edu/4826/
130
7Giles GR, Boehmig HJ, Lilly J, Amemiya H, Takagi H, Coburg AJ, Hathaway WE, Wilson CB, Dixon FJ, Starzl TE: Mechanism and modification of rejection of heterografts between divergent species. Transplant Proc 2:522-538, 1970.
http://d-scholarship.pitt.edu/3612/
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8 Starzl TE: History of Clinical Transplantation. World J Surg 24:759-782, 2000. (Also published verbatim in: Starzl TE: A History of Clinical Transplantation. In: Surgery: Basic Science and Clinical Evidence. (eds. JA Norton, R Bollinger, AE Chang, SJ Mulvihill, S Lowry, H Pass, R Thompson). Springer Verlag, New York, NY. 2001 and 2008, 1st and 2nd editions).
http://d-scholarship.pitt.edu/5507/
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9Starzl TE, Valdivia LA, Murase N, Demetris AJ, Fontes P, Rao AS, Manez R, Marino I, Todo S, Thomson AW, Fung JJ: The biologic basis of and strategies for clinical xenotransplantation. Immunol Rev 141:213-244, 1994.
http://d-scholarship.pitt.edu/5062/
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10Giles GR, Boehmig HJ, Amemiya H, Halgrimson CG, Starzl TE: Clinical heterotransplantation of the liver. Transplant Proc 2:506-512, 1970.
http://d-scholarship.pitt.edu/3609/
35
11Michaels MG, McMichael JP, Brasky K, Kalter S, Peters RL, Starzl TE, Simmons RL: Screening donors for xenotransplantation: the potential for xenozoonoses. Transplantation 57:1462-1465, 1994.
http://d-scholarship.pitt.edu/5015/
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12Makowka L, Miller C, ChapChap P, Podesta L, Pan C, Pressley D, Mazzaferro V, Esquivel CO, Todo S, Banner B, Jaffe R, Saunders R, Starzl TE: Prolongation of pig to dog renal xenograft survival by modification of the inflammatory mediator response. Ann Surg 206:482 495, 1987.
http://d-scholarship.pitt.edu/4151/
34
13Starzl TE, Tzakis A, Fung JJ, Todo S, Demetris AJ, Manez R, Marino IR, Valdivia L, Murase N: Prospects of clinical xenotransplantation. Transplant Proc 26:1082-1088, 1994.
http://d-scholarship.pitt.edu/5096/
34
14Allan JS, Broussard SR, Michaels MG, Starzl TE, Leighton KL, Whitehead EM, Comuzzie AG, Lanford RE, Leland MM, Switzer WM, Heneine W: Amplification of simian retroviral sequences from human recipients of baboon liver transplants. AIDS Research & Human Retroviruses 14:821-824, 1998.
http://d-scholarship.pitt.edu/5431/
34
15Koike C, Fung JJ, Geller DA, Kannagi R, Libert T, Luppi P, Nakashima I, Profozich J, Rudert W, Sharma SB, Starzl TE, Trucco M: Molecular basis of evolutionary loss of the a1,3galactosyltransferase gene in higher primates. J Biol Chem 277:10114-10120, 2002.
http://d-scholarship.pitt.edu/5555/
34
16Kux M, Boehmig HJ, Amemiya H, Torisu M, Yokoyama T, Launois B, Popovtzer MM, Wilson CB, Dixon FJ, Starzl TE: Modification of hyperacute canine renal homograft and pig-to-dog heterograft rejection by the intra-arterial infusion of citrate. Surgery 70:103-112, 1971.
http://d-scholarship.pitt.edu/3632/
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17Valdivia LA, Fung JJ, Demetris AJ, Starzl TE: Differential survival of hamster-to-rat liver and cardiac xenografts under FK506 immunosuppression. Transplant Proc 23:3269-3271, 1991.
http://d-scholarship.pitt.edu/4697/
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18Langer A, Valdivia LA, Murase N, Woo J, Celli S, Fung JJ, Starzl TE, Demetris AJ: Humoral and cellular immunopathology of hepatic and cardiac hamster-into-rat xenograft rejection: marked stimulation of IgM+ +bright/IgD+dull splenic B cells. Am J Pathol 143(1):85-98, 1993.
http://d-scholarship.pitt.edu/4986/
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19Michaels MG, Lanford R, Demetris AJ, Chavez D, Brasky K, Fung J, Starzl TE: Lack of susceptibility of baboons to infection with hepatitis B virus. Transplantation 61:350-351, 1996.
http://d-scholarship.pitt.edu/5260/
29
20Zeng Y, Ricordi C, Tzakis A, Rilo HRL, Carroll PB, Starzl TE, Ildstad ST: Long term survival of donor-specific pancreatic islet xenografts in fully xenogeneic chimeras (WF rat B10 mouse). Transplantation 53:277-283, 1992.
http://d-scholarship.pitt.edu/4727/
28
21Michaels MG, Jenkins FJ, St. George K, Nalesnik MA, Starzl TE, Rinaldo CR Jr: Detection of infectious baboon cytomegalovirus after baboon- to-human liver xenotransplantation. J Virology 75:2825-2528, 2001.
http://d-scholarship.pitt.edu/5534/
25
22Starzl TE, Demetris AJ, Murase N, Valdivia L, Thomson AW, Fung J, Rao AS: The future of transplantation: with particular reference to chimerism and xenotransplantation. Transplant Proc 29:19-27, 1997.
http://d-scholarship.pitt.edu/5304/
24
23Valdivia LA, Demetris AJ, Fung JJ, Celli S, Murase N, Starzl TE: Successful hamster to rat liver xenotransplantation under FK506 immunosuppression induces unresponsiveness to hamster heart and skin. Transplantation 55:659-661, 1993.
http://d-scholarship.pitt.edu/4828/
22
24Miyazawa H, Murase N, Demetris AJ, Matsumoto K, Nakamura K, Yee Q, Menes R, Todo S, Starzl TE: Hamster to rat kidney xenotransplantation: effects of FK506, cyclophosphamide, and organ perfusion. Transplantation 59:1183-1188, 1995.
http://d-scholarship.pitt.edu/5159/
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25Starzl TE, Rao AS, Murase N, Fung J, Demetris AJ: Will xenotransplantation ever be feasible? J Am Coll Surg 186:383-387, 1998.
http://d-scholarship.pitt.edu/5395/
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26Valdivia LA, Fung JJ, Demetris AJ, Celli S, Pan F, Tsugita M, Starzl TE: Donor species complement after liver xenotransplantation: Mechanism of protection from hyperacute rejection. Transplantation 57:918-922, 1994.
http://d-scholarship.pitt.edu/4941/
20
27Merkel FK, Bier M, Beavers CD, Merriman WG, Wilson C, Starzl TE: Modification of xenograft response by selective plasmapheresis. Transplant Proc 3:534-537, 1971.
http://d-scholarship.pitt.edu/3619/
19
28Koike C, Uddin M, Wildman DE, Gray EA, Trucco M, Starzl TE, Goodman M: Functionally important glycosyltransferase gain and loss during catarrhine primate emergence. Proc Natl Acad Sci 104:559-564, 2007.
http://d-scholarship.pitt.edu/5618/
19
29Celli S, Valdivia LA, Fung JJ, Demetris AJ, Marino IR, Murase N, Starzl TE: Long-term survival of heart and liver xenografts with splenectomy and FK506. Transplant Proc 25:647-648, 1993.
http://d-scholarship.pitt.edu/4911/
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30Lanford RE, Michaels MG, Chavez D, Brasky K, Fung J, Starzl TE: Persistence of extrahepatic Hepatitis B virus DNA in the absence of hepatic replication in patients with baboon liver transplants. J Med Virol 46:207-212, 1995.
http://d-scholarship.pitt.edu/5170/
17
31Tanaka M, Murase N, Ye Q, Miyazaki W, Nomoto M, Miyazawa H, Manez R, Toyama Y, Demetris AJ, Todo S, Starzl TE: The effect of anti-complement agent K76 COOH on hamster and guinea pig to rat heart xenotransplantation. Transplantation 62:681-688, 1996.
http://d-scholarship.pitt.edu/5271/
16
32Groth CG, Brent LB, Calne RY, Dausset JB, Good RA, Murray JE, Shumway NE, Schwartz RS, Starzl TE, Terasaki PI, Thomas ED, van Rood JJ: Historical landmarks in clinical transplantation: conclusions from the concensus conference at the University of California, Los Angeles (UCLA). World J Surg 24:834-843, 2000.
http://d-scholarship.pitt.edu/5497/
14
33Ikeda T, Yanaga K, Lebeau G, Higashi H, Kakizoe S, Starzl TE: Hemodynamic and biochemical changes during normothermic and hypothermic sanguinous perfusion of the porcine hepatic grafts. Transplantation 50:564-567, 1990.
http://d-scholarship.pitt.edu/4493/
14
34Starzl TE, Murase N, Demetris AJ, Ildstad S, Ricordi C, Trucco M: Allograft and xenograft acceptance under FK506 and other imunnosuppressive treatment. NY Academy Sci 685:46-51, 1993.
http://d-scholarship.pitt.edu/4891/
14
35Koike C, Friday RP, Nakashima I, Luppi P, Fung JJ, Rao AS, Starzl TE, Trucco M: Isolation of the regulatory regions and genomic organization of the porcine α1,3-galactosyltransferase gene. Transplantation 70:1275-1283, 2000.
http://d-scholarship.pitt.edu/5513/
14
36Starzl TE: Liver allo- and xenotransplantation Transplant Proc 25:15-17, 1993.
http://d-scholarship.pitt.edu/4864/
13
37Ricordi C, Zeng Y, Carroll PB, Rilo HLR, Beretier DB, Starzl TE, Ildstad ST: Islet xenografts in fully xenogeneic(Rat --> mouse) chimeras: evidence for normal regulation of function in a xenogeneic mouse environment. Surgery 112:327-332, 1992.
http://d-scholarship.pitt.edu/4780/
10
38Valdivia LA, Lewis JH, Celli S, Bontempo FA, Fung JJ, Demetris AJ, Starzl TE: Hamster coagulation and serum proteins in rat recipients of hamster xenografts. Transplantation 56:489-490, 1993.
http://d-scholarship.pitt.edu/4879/
10
39Murase N, Demetris AJ, Tanabe M, Miyazawa H, Valdivia LA, Nakamura K, Starzl TE: Effect of FK 506 and antiproliferative agents for heart and liver xenotransplantation from hamster to rat. Transplant Proc 25:425-426, 1993.
http://d-scholarship.pitt.edu/4880/
9
40Imventarza O, Todo S, Eiras G, Ueda Y, Furukawa H, Wu YM, Zhu Y, Oks A, Demetris AG, Starzl TE: Renal transplantation in baboons under FK 506. Transplant Proc 22:64-65, 1990.
http://d-scholarship.pitt.edu/4465/
8
41Miki T, Goller A, Rao A, Wang X, Yin WY, Tandin A, Fung JJ, Starzl TE, Valdivia LA: Tacrolimus enhances the immunosuppressive effect of cyclophosphamide but not that of leflunomide for mycophenolate mofetil in a model of discordant liver xenotransplantation. Transplant Proc 30:1091-1092, 1998.
http://d-scholarship.pitt.edu/5429/
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42Valdivia LA, Sun H, Rao AS, Tsugita M, Chen CT, Park I-Y, Fung JJ, Starzl TE: Donor-specific transfusion in the nude rat prolongs survival of subsequently transplanted hamster cardiac xenografts. Transplant Proc 29:928-929, 1997.
http://d-scholarship.pitt.edu/5305/
7
43Starzl TE, Rao A, Murase N, Demetris AJ, Thomson A, Fung JJ: Chimerism and xenotransplantation. New concepts. Surgical Clinics of North America: Liver Transplantation - Current Management. (eds. J Fung, J Rakela) W.B. Saunders Company, Philadelphia, PA 79:191-205, 1999.
http://d-scholarship.pitt.edu/5415/
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44Ricordi C, Tzakis AG, Rybka WB, Fontes P, Ball ED, Trucco M, Kocova M, Triulzi D, McMichael J, Doyle H, Gupta P, Fung JJ, Starzl TE: Xenotransplantation of hematopoietic cells resistant to HIV as a potential treatment for patients with AIDS. Transplant Proc 26:1302-1303, 1994.
http://d-scholarship.pitt.edu/5095/
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45Triulzi DJ, Jochum EE, Marino IR, Starzl TE: Heteroagglutinins and their significance in baboon hepatic xenotransplantation. Transplantation 60:127-131, 1995.
http://d-scholarship.pitt.edu/5164/
6
46Celli S, Valdivia LA, Fung JJ, Kelly RH, Pan F, Tsugita M, Demetris AJ, Starzl TE: Metabolic changes in the recipient after successful liver xenotransplantation in the rat. Transplant Proc 26:1207, 1994.
http://d-scholarship.pitt.edu/578/
5
47Miyazawa H, Murase N, Demetris AJ, Nakamura K, Matsumoto K, Ye Q, Manez R, Todo S, Starzl TE: Mechanisms of hamster kidney graft rejection in rat. Transplant Proc 26:1205-1206, 1994.
http://d-scholarship.pitt.edu/5090/
5
48Nardo B, Valdivia LA, Pan F, Celli S, Tsugita M, Demetris AJ, Fung JJ, Starzl TE: Pretransplant xenogeneic blood transfusion combined with FK506 prolongs hamster-to-rat liver xenograft survival. Transplant Proc 26:1208, 1994.
http://d-scholarship.pitt.edu/5093/
5
49Fontes P, Rao AS, Ricordi C, Zeevi A, Kocova M, Rybka WB, Ukah FO, Mullen E, Vasko C, Trucco M, Demetris AJ, Fung JJ, Starzl TE: Human to baboon bone marrow transplantation after conditioning with non-lethal irradiation. Transplant Proc 26:3367-3368, 1994.
http://d-scholarship.pitt.edu/5067/
4
50Rastellini C, Carroll PB, Rilo HLR, Fontes P, Behboo R, Rao AS, Ricordi C, Starzl TE: Baboon pancreatic islet isolation and transplantation. Transplant Proc 26:3428-3429, 1994.
http://d-scholarship.pitt.edu/5068/
4
51Tsugita M, Valdivia LA, Rao AS, Pan F, Celli S, Demetris AJ, Fung JJ, Starzl TE: Tacrolimus pretreatment attenuates pre-existing xenospecific immunity and abrogates hyperacute rejection in a presensitized hamster ® rat liver transplant model. Transplantation 61(12):1730-1735, 1996.
http://d-scholarship.pitt.edu/5249/
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52Zeng Y, Ildstad ST, Rilo HLR, Beretier DR, Carroll PB, Tzakis AG, Starzl TE, Ricordi C: Long term survival of donor-specific pancreatic islet xenografts in fully xenogeneic chimeras (F344 Rat to Bio Mouse). Transplant Proc 24:641, 1992.
http://d-scholarship.pitt.edu/4722/
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53Valdivia LA, Demetris AJ, Fung JJ, Celli S, Frye C, Murase N, Starzl TE: Hamster-to-rat liver xenografts protect extrahepatic organs from rejection. Transplant Proc 25:414-415, 1993.
http://d-scholarship.pitt.edu/4881/
3
54Tanaka M, Murase N, Miyazawa H, Ye Q, Manez R, Todo S, Demetris AJ, Nomoto M, Miyazaki W, Starzl TE: Effect of anticomplement of agent K-76 COOH in hamster-to-rat and guinea pig-to-rat xenotransplantation. Transplant Proc 27:275-276, 1995
http://d-scholarship.pitt.edu/5135/
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55Celli S, Kelly RH, Rao AS, Pan F, Sun H, Nalesnik M, Wakizaka Y, Fung JJ, Starzl TE, Valdivia LA: The antigenicity of serum proteins and their role in xenograft rejection. Transplant Proc 28:669-670, 1996.
http://d-scholarship.pitt.edu/5220/
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56Sun H, Wakizaka Y, Rao AS, Pan F, Madariaga J, Yark IlY, Celli S, Fung JJ, Starzl TE, Valdivia LA: The use of MHC class I or class II “knock out” mice to delineate the role of these molecules in the acceptance/rejection of xenografts. Transplant Proc 28:732, 1996.
http://d-scholarship.pitt.edu/5224/
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57Tsugita M, Rao AS, Sun H, Wakizaka Y, Madariaga J, Pan F, Demetris AJ, Fung JJ, Starzl TE, Valdivia LA: Pretreatment of recipients (nude rat) with donor antigens leads to prolonged survival of hamster heart xenografts. Transplant Proc 28:696-697, 1996.
http://d-scholarship.pitt.edu/5221/
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58Koike C, Friday R, Fung JJ, Starzl TE, Trucco M: Comparison of the regulatory regions of the a1,3Galactosyltransferase gene between murine and porcine species. Transplant Proc 33:710-711, 2001.
http://d-scholarship.pitt.edu/5543/
3
59Ricordi C, Zeng Y, Carr B, Carroll P, Rilo HLR, Demetris AJ, Alejandro R, Bereiter DR, Fung JJ, Tzakis A, Starzl TE: Survival of human hepatocellular aggregates in athymic mice. Transplant Proc 24:986, 1992.
http://d-scholarship.pitt.edu/4806/
2
60Celli S, Valdivia LA, Kelly RH, Sun H, Tsugita M,. Pan F, Rao AS, Demetris AJ, Fung JJ, Starzl TE: Mechanisms of protection from humoral rejection by a xenografted liver. Transplant Proc 27:300-302, 1995.
http://d-scholarship.pitt.edu/5117/
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61Pan F, Tsugita M, Rao AS, Wakizaka Y, Sun H, Park Il-Y, Fung JJ, Starzl TE, Valdivia LA: Effect of tacrolimus and splenectomy on engraftment and GVHD after bone marrow xenotransplantation in the reciprocal hamster rat animal models. Transplant Proc 28:736-737, 1996.
http://d-scholarship.pitt.edu/5225/
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62Valdivia LA, Sun H, Rao AS, Tsugita M, Pan F, Wakizaka Y, Miki T, Demetris AJ, Fung JJ, Starzl TE: Prolonged survival of hearts obtained from chimeric donors in a mouse ® rat xenotransplant model. Transplant Proc 28:733-734, 1996.
http://d-scholarship.pitt.edu/5222/
2
63Ye Q, Murase N, Tanaka M, Demetris AJ, Manez R, McCauley J, Todo S, Starzl TE: Functional analysis of hamster kidney xenografts in the rat: possible functional incompatibility and adaptation of hamster kidney graft in xenogenic rat environment. Transplant Proc 28:694-695, 1996.
http://d-scholarship.pitt.edu/5246/
2
64Valdivia LA, Sun H, Rao AS, Tsugita M, Chen CT, Park I-Y, Fung JJ, Starzl TE: Donor-specific transfusion in the nude rat prolongs survival of subsequently transplanted hamster cardiac xenografts. Transplant Proc 29:928-929, 1997. http://d-scholarship.pi
http://d-scholarship.pitt.edu/5305/
2